Targeting Phosphorylcholine in Established Atherosclerosis?
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چکیده
منابع مشابه
Chemokines: established and novel targets in atherosclerosis
In their role as small chemotactic cytokines, chemokines are crucial mediators and regulators of leukocyte trafficking during immune surveillance and inflammation. Their involvement in the development and progression of inflammatory diseases has been subject of intense investigation. Concordantly, the chemokine system has been explored in search for therapeutic targets to prevent or treat infla...
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957 Letter to the Editor Nonbone Marrow–Derived Endothelial Progenitor Cells: What Is Their Exact Location? Alexandra Aicher, Stefanie Dimmeler, Christopher Heeschen Web Site Feature e102 On the cover: The image shows on the left the formation of the pulmonary myocardial sleeves by rapid proliferation of the just-differentiated myocardium (section of an E12.5 embryo stained for BrdU (red), cTnI...
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The chronic inflammatory nature of atherosclerotic disease is now widely appreciated. Abnormal deposition and oxidative modification of serum lipoproteins in arterial walls stimulates the recruitment of monocytes and their conversion into foam cells. Concurrently, both innate and adaptive immune responses are induced. Cytokines and growth factors produced as part of these responses lead to the ...
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Chance, B. (1948). Nature, Lond., 161, 914. Chance, B. (1949a). Science, 109, 204. Chance, B. (1949b). J. biol. Chem. 180, 947. Chance, B. (1950). J. biol. Chem. 182, 649. Chance, B. (1952a). J. biol. Chem. 194, 471. Chance, B. (1952b). Arch. Biochem. Biophys. 41, 416. Chance, B., Greenstein, D. S. & Roughton, F. J. W. (1952). Arch. Biochem. Biophy8. 37, 301. Chodat, R. & Bach, A. (1903). Ber. ...
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BACKGROUND Antibodies against cardiolipin and phosphatidylserine (anti-CL and anti-PS) are associated with thrombosis. In contrast, we determined that IgM antibodies against oxidized CL and PS (OxCL and OxPS) and phosphorylcholine (anti-PC) could be protection markers for cardiovascular disease (CVD). METHODS 226 individuals with established hypertension (diastolic pressure>95 mmHg) from the ...
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ژورنال
عنوان ژورنال: JACC: Basic to Translational Science
سال: 2020
ISSN: 2452-302X
DOI: 10.1016/j.jacbts.2020.03.005